Chromicent has enhanced its portfolio with size exchange chromatography (SEC). This chromatographic method enables us to separate molecules in solution by size (hydrodynamic volume) and to identify their relative molecular weight. The use of SEC in our laboratory routine serves the characterization of proteins, synthetic polymers and natural polymers, such as polysaccharides.
The ability to analyze multimers (dimers, trimers, polymers) particularly supports our work in the field of impurities of ingredients, e.g. in cases where separation with classical RP-chromatography is not sufficiently successful, or in the highly sensible and topical field of extractables and leachables in drugs or their packaging.
Another important keyword is: bioanalytics. Being able to detect macromolecules – i.e. proteins, carbohydrates and lipids, but also DNA and RNA – and potential changes to them is another issue of the future. An issue Chromicent is prepared for. We keep you updated.